科学家发现逆转肥胖的天然激素
一种名为 FGF21 的激素可以通过激活新发现的与新陈代谢相关的大脑回路来逆转小鼠的肥胖。令人惊讶的是，它在后脑中起作用——与 Ozempic 和 Wegovy 等 GLP-1 药物的目标区域相同——但通过完全...
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来源: Science Daily
A hormone called FGF21 can reverse obesity in mice by activating a newly identified brain circuit tied to metabolism. Surprisingly, it works in the hindbrain—the same region targeted by GLP-1 drugs like Ozempic and Wegovy—but through a completely different mechanism. Instead of suppressing appetite, FGF21 ramps up the body’s energy burning. This insight could pave the way for more targeted weight-loss and liver disease treatments.
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